Application of Compass system in three-dimensional dose verification of preoperative intensity-modulated radiotherapy plan for rectal cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2017年第12期
- Page:
- 1200-1205
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Application of Compass system in three-dimensional dose verification of preoperative intensity-modulated radiotherapy plan for rectal cancer
- Author(s):
- 段隆焱; 蔡钢; 陈毅; 张毅斌; 沈文同
- CHANG Xue, WANG Kun, ZHANG Jian, JIN Sunjun, WANG Zhipeng
- Keywords:
- rectal cancer; Compass system; intensity-modulated radiotherapy; dose verification; preoperative radiotherapy
- PACS:
- R815.6
- DOI:
- DOI:10.3969/j.issn.1005-202X.2017.12.003
- Abstract:
- Abstract: Objective To investigate the clinical application of Compass system in the three-dimensional (3D) dose verification of preoperative intensity-modulated radiotherapy (IMRT) plan for patients with rectal cancer. Methods Ten preoperative IMRT plans for rectal cancer were optimized with Pinncale 9.10 treatment planning system (TPS). The irradiation field in plans was seven fields showing fan-shaped distribution. Two kinds of dose verification methods in Compass system, namely dose calculation and dose reconstruction, were separately used to obtain computed dose distribution (CDD) and reconstructed dose distribution (RDD) for verifying the Gamma passing rate, D95%, D50%, D2%, and Dmean of the planning target volume (PTV) and organs-at-risk. Results The Gamma passing rates of PTV and organs-at-risk from CDD-TPS were greater than 98.5%, meanwhile, the rates from CDD-TPS were higher than those from RDD-TPS. The differences between CDD-TPS and RDD-TPS in the Gamma passing rates of PTV and bladder were statistically significant (t=2.731, 2.298; P<0.05). The D2% of PTV and the Dmean of the bladder and the right femoral head between CDD-TPS and RDD-TPS were also statistically significant (t=-4.280, -2.582, -2.582; P<0.05). Compared with RDD-TPS, CDD-TPS showed greater D50%, D2% of PTV and Dmean of the left and right femoral head. Conclusion The dose verification and evaluation methods, three-dimensional dose deviation and Gamma passing rate provided by Compass system can reasonably verify the preoperative IMRT plan for rectal cancer, with clinical significance.
Last Update: 2017-12-20