Abstract

Info

Title:: Application of multi-slice spiral CT perfusion parameters in the evaluation of curative effect of TACE for hepatocellular carcinoma

Keywords:: ; hepatocellular carcinoma; transcatheter arterial chemoembolization; multi-slice spiral computed tomography; perfusion parameters; lipiodol deposition

Abstract:: Objective To investigate the application of multi-slice spiral computed tomography (MSCT) perfusion parameters in evaluating the therapeutic effect of transcatheter arterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC). Methods Ninety-four patients with HCC admitted to Songzi People’s hospital from January 2015 to December 2016 were selected. All patients were treated with Seldinger femoral artery catheterization, underwent digital subtraction angiography and TACE, and received MSCT in the preoperative and postoperative examinations. Results The lipiodol deposition in MSCT scan revealed that for type I, the number of mass type was less than that of nodular type (18/54 vs 28/40, P<0.05), while for type II, the number of mass type was more than that of nodular type (30/54 vs 10/40, P<0.05). No statistical differences were found in type III and type IV (P>0.05). The total effective rates of mass and nodular HCC were 90.74% (49/54) and 92.50% (37/40), respectively. Conclusion MSCT perfusion parameters can be used to evaluate the efficacy of TACE in patients with HCC, with good application value in clinic.