CT enhancement features of pleomorphic adenoma in submandibular gland and comparison with pathological results
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2017年第12期
- Page:
- 1236-1240
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- CT enhancement features of pleomorphic adenoma in submandibular gland and comparison with pathological results
- Author(s):
- LIU Xianwei1; ZHAN Qing2; ZHAO Jiangmin1
- 1. Department of Radiology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, China; 2. Department of Neurology and Rehabilitation, Shanghai Seventh People’s Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200137, China
- Keywords:
- ; Keywords: submandibular gland; pleomorphic adenoma; enhanced CT; pathology
- PACS:
- R739.87；R445.3
- DOI:
- DOI:10.3969/j.issn.1005-202X.2017.12.009
- Abstract:
- Abstract: Objective To explore enhanced CT findings of pleomorphic adenoma in submandibular gland (PAS) and compare those findings with pathologic results for improving the diagnostic accuracy of enhanced CT image for PSA. Methods The clinical manifestations and enhanced dual-phase CT findings of 22 patients with surgically and pathologically confirmed PAS were analyzed retrospectively. The location, number, size, morphology, border, CT density, enhancement pattern and CT quantitative diagnostic index were comprehensively analyzed. Results Among the 22 selected cases, left PAS was found in 9 cases and right PAS in 13 cases; 17 cases located in the superficial lobe of submandibular gland, 3 cases in the deep lobe of submandibular gland, and 2 cases involved both superficial and deep lobes; only 1 case was unilateral and multiple, and the others were unilateral and solitary. The maximum transverse diameter of tumor was 1.0-4.7 cm, with a mean diameter at 2.3 cm. The lesions were mostly round-like or oval soft tissue mass with clear boundary. The CT plain scan density were homogeneous in 6 cases (6/22) and heterogeneous in the others (16/22) where hypodensity cystic masses of different sizes were found, and among them, punctate or patchy calcifications were found in 3 cases. The solid components of 16 cases (16/22) were isodensity, and the other 6 cases (6/22) were mild hypodensity, compared with the density of masseter at the same layer. On arterial phase images, the CT value was about (59.9±12.6) HU and on venous phase image, the solid components kept enhanced and the CT value was about (71.1±13.5) HU. The statistical analysis showed that no enhancement in 2 cases (2/22), mild to moderate enhancement in 17 cases (17/22), and remarkable enhancement in 3 cases (3/22), which indicated that most of solid components of PAS were progressively enhanced (mild to moderate). Conclusion PAS is the most common benign tumor at submandibular gland, mostly occurred in females aged over 40 years old, and often only involved the lower boundary part of submandibular gland. In most cases, the lesions were presented as round-like soft tissue mass with clear boundary. The CT plain scan showed various densities, and some cystic necrosis and calcification in the interior of tumor. After enhancement, the tumor appears some CT enhancement features, such as clear tumor capsule, no abundant blood supply to the tumor, and progressively enhancement (mild to moderate) in most of the solid components of tumor. The comprehensive consideration of the medical history and clinical manifestations is helpful for improving the diagnostic accuracy of PAS.
Last Update: 2017-12-21