Abstract

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Title:: Application of mixtures of gelatin sponge and lidocaine in preventing bone cement leakage during vertebroplasty

Author(s):: WEI Hanyu; PENG Xiaozhong; YANG Zhixian; Department of Spinal Surgery, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou 545005, China

Abstract:: Objective To study the effect of pre-injection of the mixtures of gelatin sponge and lidocaine in percutaneous vertebroplasty (PVP) on postoperative therapeutic effect and bone cement leakage. Methods Seventy-four patients undergoing PVP were selected and randomly divided into observation group and control group. Patients in observation group were injected with the mixtures of gelatin sponge and lidocaine before the bone cement injection, while those in control group received conventional PVP and was injected with bone cement directly after acupuncture. Results The 3 days to 1 month of follow-up after operation showed that the scores of visual analogue scale in observation group were significantly lower than those in control group (P<0.05). In 1 year after operation, the Oswestry disability index (ODI) score of observation group was (14.6±5.0), significantly lower than (23.1±4.4) of control group; and the incidences of vertebral refracture in control group and observation group were 3.77% and 0.00%, respectively. Two cases in observation group appeared type S leakage, while control group had 2 cases of type B leakage, 3 cases of type C leakage and 2 cases of type S leakage, with a total leakage rate of 13.2%. Conclusion The pre-injection of mixtures of gelatin sponge and lidocaine can effectively reduce the incidence of bone cement leakage in vertebroplasty and has better efficacy in alleviating patient’s pain, worth of popularizing in the clinic.